Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation

Abstract Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis.Both genetic and lifestyle factors, particularly diet and nutrition, contribute to its etiology.Folate deficiency, a frequently enc

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Applicability of Convex and Concave Shaped Surface Texturing to Improve Damping Performance of Mechanical Tensioner for Timing Chain of Internal Combustion Engine

The present study describes an improvement of damping performance of a mechanical tensioner driven by friction force at the power spring interface, used for the timing chain system for an internal combustion engine.The mechanical tensioner consists of a power spring subjected to umcka where to buy face-to-face contact with a reciprocal motion and a

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